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Research Associate

Biomedical & Life Sciences
Salary:   £27,285 to £31,604
Closing Date:   Wednesday 15 November 2017
Interview Date:   Wednesday 29 November 2017
Reference:  A2108

We are looking for a postdoctoral researcher to join our team to investigate the innate immune response to DNA damage in human cells, in the laboratory of Dr Leonie Unterholzner in the Division of Biomedical and Life Sciences at Lancaster University, UK. This is a 12 months fixed term position funded by the Medical Research Council and North West Cancer Research. 

Our lab investigates how cells detect intracellular DNA during infection and injury, as part of the innate immune response (see Almine et al., 2017, Nature Communications 8:14392). In addition to detecting foreign DNA in the cytosol, the innate immune system can also detect viral DNA and DNA damage in the nucleus. In this project we will investigate how nuclear DNA damage is detected by the innate immune system, and how the innate immune DNA sensors interact with the DNA damage repair machinery in human cells. 

Candidates are required to have been recently awarded a PhD in a relevant field, or be close to completion, and have a strong background in molecular and cell biology techniques. A good working knowledge of the DNA damage response and innate immune signalling is required. Experience in the analysis of post-translational modifications and protein-protein interactions would be an advantage. We are looking for a highly motivated individual with excellent communication skills, the capacity to work well in a team and the ability to solve problems creatively. 

Our lab and the Division of Biomedical and Life Sciences is a friendly research environment that strongly supports the individual needs of each employee and which actively promotes a healthy work-life balance. The Faculty is committed to family-friendly and flexible working policies and has held a Silver Athena SWAN award since 2014 in recognition of its good employment practice undertaken to address gender equality in higher education and research.

Informal enquiries are welcome. Please contact Dr Leonie Unterholzner ( for more information. 

We welcome applications from people in all diversity groups. 

The closing date for this job opportunity has now passed, and applications are no longer being accepted for this position

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